OpenAPS의 기능
Autosens
Autosens is an algorithm which looks at blood glucose deviations (positive/negative/neutral).
이 기능은 혈당 편차에 근거하여 사용자가 얼마나 인슐린에 민감한지, 저항성을 띄는지를 파악할 것입니다.
OpenAPS에서 Oref 구현은 24시간, 8시간 동안의 데이터를 조합하여 실행됩니다. 두 가지 데이터 중 민감도가 더 높은 것을 사용합니다.
In versions prior to AAPS 2.7, the user had to choose between 8 or 24 hours manually.
From AAPS 2.7 on Autosens in AAPS will switch between a 24 and 8 hours window for calculating sensitivity. It will pick whichever one is more sensitive.
사용자가 oref1을 사용했을 경우, 8시간 또는 24시간의 민감도 변경으로 인하여 시스템이 변화에 덜 역동적임을 인지할 수 있을 것입니다.
Changing a cannula or changing a profile will reset Autosens ratio back to 100% (a percentual profile switch with duration won’t reset autosens).
Autosens adjusts your basal and ISF (i.e.: mimicking what a Profile shift does).
If continuously eating carbs over an extended period, Autosens will be less effective during that period as carbs are excluded from BG delta calculations.
Super Micro Bolus (SMB)
SMB, the shortform of Super micro bolus, is an OpenAPS feature introduced from 2018 onwards, within the Oref1 algorithm. In contrast to AMA, SMB does not use temporary basal rates to control glucose levels, but mainly small super micro boluses. In situations where AMA would add 1.0 IU insulin using a temporary basal rate, SMB delivers several super micro boluses in small steps at 5 minute intervals, e.g. 0.4 IU, 0.3 IU, 0.2 IU and 0.1 IU. At the same time (for safety reasons) the actual basal rate is set to 0 IU/h for a certain period to prevent overdose (‘zero-temping’). This allows the system to adjust the blood glucose faster than with the temporary basal rate increase in AMA.
Thanks to SMB, it may be sufficient for meals containing only “slow” carbs to inform the system of the planned amount of carbohydrate and leave the rest to AAPS. However, this may lead to higher postprandial (post-meal) peaks because pre-bolusing isn’t possible. Or you can give, if necessary with pre-bolusing, a start bolus, which only partly covers the carbohydrates (e.g. 2/3 of the estimated amount) and let SMB deliver the rest of the insulin.
SMBs are shown on the main graph with blue triangles. Tap on the triangle to see how much insulin was delivered, or use the Treatments tab.
SMB’s features contain some safety mechanisms:
Largest single SMB dose
The largest single SMB dose can only be the smallest value of:“SMB 제한을 위한 최대 시간”으로 설정된 시간 동안의 (autosens에 의해 조정된) 현재 basal 양에 따른 값, 즉, 다음 30분 동안의 basal 총량,
또는, 현재 필요한 인슐린의 양의 절반
또는, 설정의 maxIOB 값에서 남아있는 양
Low temp basal rates
Low temporary basal rates (called ‘low temps’) or temporary basal rates at 0 U/h (called ‘zero-temps’) are activated more in SMB. This is by design for safety reasons and has no negative effects if the Profile is set correctly. On the main graph, the IOB curve (yellow thin line) is more meaningful than the course of the temporary basal rates.Un-Announced Meals
Additional calculations to predict the course of glucose, e.g. by UAM (un-announced meals). Even without manual carbohydrate input from the user, UAM can automatically detect a significant increase in glucose levels due to meals, adrenaline or other influences and try to adjust this with SMB. 안전 측면에서 이는 반대로 작동하며, 예상치 못한 혈당의 급격한 감소가 발생하는 경우 SMB를 일찍 중단할 수 있습니다. 이것이 SMB 사용 시 UAM이 항상 활성화되어야 하는 이유입니다.
You must have started objective 9 to use SMB.
See also :
The settings for OpenAPS SMB are described below.
Max U/h a temp basal can be set to
This safety setting determines the maximum temporary basal rate the insulin pump may deliver. It is also known as max-basal.
The value is measured in units per hour (U/h). It is advised to set this to something sensible. A good recommendation for setting this parameter is:
max-basal = highest basal rate x 4
For example, if the highest basal rate in your profile was 0.5 U/h you could multiply that by 4 to get a value of 2 U/h.
AAPS limits this value as a ‘hard limit’ according to Preferences > Treatments safety > Patient Type. The hard limits are as follows:
어린이: 2
Teenager: 5
성인: 10
인슐린 저항성이 있는 성인: 12
Pregnant: 25
See also overview of hard-coded limits.
Maximum total IOB OpenAPS can’t go over
This value determines the maximum Insulin on Board (basal and bolus IOB) that AAPS will remain under while running in closed loop mode. It is also known as maxIOB.
If the current IOB (e.g. after a meal bolus) is above the defined value, the loop stops dosing insulin until the IOB limit is below the given value.
A good start for setting this parameter is:
maxIOB = 평균 식사 bolus + 하루 최대 basal의 3배 양
Be careful and patient when adjusting your max-IOB. It is different for everyone and can also depend on the average total daily dose (TDD).
AAPS limits this value as a ‘hard limit’ according to Preferences > Treatments safety > Patient Type. The hard limits are as follows:
Child: 3
Teenager: 7
Adult: 12
Insulin resistant adult: 25
Pregnant: 40
See also overview of hard-coded limits.
Note : When using SMB, the max-IOB is calculated differently than in AMA. In AMA, maxIOB is a safety-parameter for basal IOB, while in SMB-mode, it also includes bolus IOB.
See also OpenAPS documentation for SMB.
Enable Autosens
Autosens looks at blood glucose deviations (positive/negative/neutral). It will try and figure out how sensitive/resistant you are based on these deviations and adjust basal rate and ISF based on these deviations.
SMB를 사용하기
Enable this to use SMB functionality. If disabled, no SMBs will be given.
Enable SMB with high temp targets
If this setting is enabled, SMBs will still be delivered even if the user has selected a high Temp Target (defined as anything above 100mg/dL or 5.6mmol/l, regardless of Profile target). This option is intended to be used to disable SMBs when the setting is disabled. For example, if this option is disabled, SMBs can be disabled by setting a Temp Target above 100mg/dL or 5.6mmol/l. This option will also disable SMBs regardless of what other condition is trying to enable SMB.
If this setting is enabled, SMB will only be enabled with a high temp target if Enable SMB with temp targets is also enabled.
Enable SMB always
If this setting is enabled, SMB is enabled always enabled(independent of COB, temp targets or boluses). If this setting is enabled, the rest of the enable settings below will have no effect. However, if Enable SMB with high temp targets is disabled and a high temp target is set, SMBs will be disabled.
For safety reasons, this option is only available for BG sources with a good filtering system for noisy data.
Currently, it is only available with a Dexcom G5 or G6, if using the Build your own Dexcom App or “native mode” in xDrip+. If a BG value has too large of a deviation, the G5/G6 doesn’t send it and waits for the next value 5 minutes later.
For other CGM/FGM like Freestyle Libre, SMB always is deactivated until there is a better noise smoothing plugin.
You can find more here.
Enable SMB with COB
If this setting is enabled, SMB is enabled when the COB is greater than 0.
Enable SMB with temp targets
If this setting is enabled, SMB is enabled when there is any temp target set (eating soon, activity, hypo, custom). If this setting is enabled but Enable SMB with high temp targets is disabled, SMB will be enabled when a low temp target is set (below 100mg/dL or 5.6mmol/l) but disabled when a high temp target is set.
Enable SMB after carbs
If enabled, SMB is enabled for 6h after carbohydrates are announced, even if COB has reached 0.
For safety reasons, this option is only available for BG sources with a good filtering system for noisy data.
Currently, it is only available with a Dexcom G5 or G6, if using the Build your own Dexcom App or “native mode” in xDrip+. If a BG value has too large of a deviation, the G5/G6 doesn’t send it and waits for the next value 5 minutes later.
For other CGM/FGM like Freestyle Libre, SMB always is deactivated until there is a better noise smoothing plugin.
You can find more here.
How frequently SMBs will be given in min
This feature limits the frequency of SMBs. This value determines the minimum time between SMBs. Note that the loop runs every time a glucose value comes in (generally 5 minutes). Subtract 2 minute to give loop additional time to complete. E.g. if you want SMB to be given every loop run, set this to 3 minutes.
Default value: 3 min.
Max minutes of basal to limit SMB to
This is an important safety setting. This value determines how much SMB can be given based on the amount of basal insulin in a given time, when it is covered by COBs.
Making this value larger allows the SMB to be more aggressive. You should start with the default value of 30 minutes. After some experience, increase the value in 15 minutes increments and observe the effects over multiple meals.
It is recommended not to set the value higher than 90 minutes, as this would lead to a point where the algorithm might not be able to accommodate a decreasing BG with 0 U/h basal (‘zero-temp’). You should also set alarms, especially if you are still testing new settings, which will warn you well before a hypo.
Default value: 30 min.
Enable UAM
With this option enabled, the SMB algorithm can recognize unannounced meals. This is helpful if you forget to tell AAPS about your carbs or estimate your carbs wrong and the amount of entered carbs is wrong or if a meal with lots of fat and protein has a longer duration than expected. Without any carb entry, UAM can recognize fast glucose increase caused by carbs, adrenaline, etc., and tries to adjust it with SMBs. This also works the opposite way: if there is a fast glucose decrease, it can stop SMBs earlier.
Therefore, UAM should always be activated when using SMB.
Sensitivity raises target
If this option is enabled, the sensitivity detection (autosens) can raise the target when sensitivity is detected (below 100%). In this case your target will be raised by the percentage of the detected sensitivity.
If the target is modified due to sensitivity detection, it will be displayed with a green background on your home screen.
Resistance lowers target
If this option is enabled, the sensitivity detection (autosens) can lower the target when resistance is detected (above 100%). In this case your target will be lowered by the percentage of the detected resistance.
High temp-target raises sensitivity
If you have this option enabled, the insulin sensitivity will be increased while having a temporary target above 100 mg/dl or 5.6 mmol/l. This means, the ISF will rise while IC and basal will decrease. This will effectively make AAPS less aggressive when you set a high temp target.
Low temp-target lowers sensitivity
If you have this option enabled, the insulin sensitivity will be decreased while having a temporary target lower than 100 mg/dl or 5.6 mmol/l. This means, the ISF will decrease while IC and basal will rise. This will effectively make AAPS more aggressive when you set a low temp target.
Minimal carbs required for suggestion
Minimum grams of carbs to display a carbs suggestion alert. Eating of additional carbs will be suggested when the reference design detects that it requires carbs. In this case you will receive a notification which can be snoozed for 5, 15 or 30 minutes.
Carb required notifications can be pushed to Nightscout if wished, in which case an announcement will be shown and broadcast.
In any case, the required carbs will be displayed in the COB section on your home screen.
Advanced Settings
You can read more here : OpenAPS docs.
Always use short average delta instead of simple data If you enable this feature, AAPS uses the short average delta/blood glucose from the last 15 minutes, which is usually the average of the last three values. This helps AAPS to be steadier with noisy data sources like xDrip+ and Libre.
Max daily safety multiplier This is an important safety limit. The default setting (which is unlikely to need adjusting) is 3. This means that AAPS will never be allowed to set a temporary basal rate that is more than 3x the highest hourly basal rate programmed in a user’s pump and/or profile. Example: if your highest basal rate is 1.0 U/h and max daily safety multiplier is 3, then AAPS can set a maximum temporary basal rate of 3.0 U/h (= 3 x 1.0 U/h).
Default value: 3 (shouldn’t be changed unless you really need to and know what you are doing)
Current Basal safety multiplier This is another important safety limit. The default setting (which is also unlikely to need adjusting) is 4. This means that AAPS will never be allowed to set a temporary basal rate that is more than 4x the current hourly basal rate programmed in a user’s pump and/or profile.
Default value: 4 (shouldn’t be changed unless you really need to and know what you are doing)
Advanced Meal Assist (AMA)
AMA, the short form of “advanced meal assist” is an OpenAPS feature from 2017 (oref0). OpenAPS Advanced Meal Assist (AMA) allows the system to high-temp more quickly after a meal bolus if you enter carbs reliably.
You can find more information in the OpenAPS documentation.
Max U/hr a Temp Basal can be set to (OpenAPS “max-basal”)
This safety setting helps AAPS from ever being capable of giving a dangerously high basal rate and limits the temp basal rate to x U/h. It is advised to set this to something sensible. A good recommendation is to take the highest basal rate in your profile and multiply it by 4 and at least 3. For example, if the highest basal rate in your profile is 1.0 U/h you could multiply that by 4 to get a value of 4 U/h and set the 4 as your safety parameter.
You cannot choose any value: For safety reason, there is a ‘hard limit’, which depends on the patient age. The ‘hard limit’ for maxIOB is lower in AMA than in SMB. For children, the value is the lowest while for insulin resistant adults, it is the biggest.
The hardcoded parameters in AAPS are:
어린이: 2
Teenager: 5
성인: 10
Insulin resistant adult: 12
Pregnant: 25
See also overview of hard-coded limits.
Maximum basal IOB OpenAPS can deliver [U] (OpenAPS “max-iob”)
This parameter limits the maximum of basal IOB where AAPS still works. If the IOB is higher, it stops giving additional basal insulin until the basal IOB is under the limit.
The default value is 2, but you should rise this parameter slowly to see how much it affects you and which value fits best. It is different for anyone and also depends on the average total daily dose (TDD). For safety reason, there is a limit, which depends on the patient age . The ‘hard limit’ for maxIOB is lower in AMA than in SMB.
Child: 3
Teenager: 5
Adult: 7
Insulin resistant adult: 12
Pregnant: 25
See also overview of hard-coded limits.
Enable AMA Autosens
Here, you can choose, if you want to use the sensitivity detection autosens or not.
Autosens adjust temp targets too
If you have this option enabled, autosens can adjust targets (next to basal and ISF), too. This lets AAPS work more ‘aggressive’ or not. The actual target might be reached faster with this.
Advanced Settings
Normally you do not have to change the settings in this dialogue!
If you want to change them anyway make sure to read about details in OpenAPS docs and to understand what you are doing.
Always use short average delta instead of simple data If you enable this feature, AAPS uses the short average delta/blood glucose from the last 15 minutes, which is usually the average of the last three values. This helps AAPS to work more steady with noisy data sources like xDrip+ and Libre.
Max daily safety multiplier This is an important safety limit. The default setting (which is unlikely to need adjusting) is 3. This means that AAPS will never be allowed to set a temporary basal rate that is more than 3x the highest hourly basal rate programmed in a user’s pump. Example: if your highest basal rate is 1.0 U/h and max daily safety multiplier is 3, then AAPS can set a maximum temporary basal rate of 3.0 U/h (= 3 x 1.0 U/h).
Default value: 3 (shouldn’t be changed unless you really need to and know what you are doing)
Current Basal safety multiplier This is another important safety limit. The default setting (which is also unlikely to need adjusting) is 4. This means that AAPS will never be allowed to set a temporary basal rate that is more than 4x the current hourly basal rate programmed in a user’s pump.
Default value: 4 (shouldn’t be changed unless you really need to and know what you are doing)
Bolus snooze dia divisor The feature “bolus snooze” works after a meal bolus. AAPS doesn’t set low temporary basal rates after a meal in the period of the DIA divided by the “bolus snooze”-parameter. The default value is 2. That means with a DIA of 5h, the “bolus snooze” would be 5h : 2 = 2.5h long.
Default value: 2
Overview of hard-coded limits
Child |
Teenager |
Adult |
Insulin resistant adult |
Pregnant |
|
---|---|---|---|---|---|
MAXBOLUS |
5,0 |
10,0 |
17,0 |
25,0 |
60,0 |
MINDIA |
5,0 |
5,0 |
5,0 |
5,0 |
5,0 |
MAXDIA |
9,0 |
9,0 |
9,0 |
9,0 |
10,0 |
MINIC |
2,0 |
2,0 |
2,0 |
2,0 |
0,3 |
MAXIC |
100,0 |
100,0 |
100,0 |
100,0 |
100,0 |
MAXIOB_AMA |
3,0 |
5,0 |
7,0 |
12,0 |
25,0 |
MAXIOB_SMB |
7,0 |
13,0 |
22,0 |
30,0 |
70,0 |
MAXBASAL |
2,0 |
5,0 |
10,0 |
12,0 |
25,0 |